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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2005 1
2007 1
2008 1
2009 2
2010 2
2012 2
2013 1
2015 2
2016 1
2018 1
2019 2
2020 2
2023 1
2024 1

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17 results

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Page 1
Pharmacogenetics of the Primary and Metastatic Osteosarcoma: Gene Expression Profile Associated with Outcome.
Trujillo-Paolillo A, Tesser-Gamba F, Seixas Alves MT, Filho RJG, Oliveira R, Petrilli AS, Toledo SRC. Trujillo-Paolillo A, et al. Int J Mol Sci. 2023 Mar 15;24(6):5607. doi: 10.3390/ijms24065607. Int J Mol Sci. 2023. PMID: 36982681 Free PMC article.
In addition, the expression of the ABCC10, GGH, GSTM3 and SLC22A1 genes were associated with the disease event, and the metastasis specimens showed a high expression profile of ABCC1, ABCC3 and ABCC4 genes and a low expression of SLC22A1 and ABCC10 genes, which is possibly …
In addition, the expression of the ABCC10, GGH, GSTM3 and SLC22A1 genes were associated with the disease event, and the metastasis specimens …
Expression of genes involved in xenobiotic metabolism and transport in end-stage liver disease: up-regulation of ABCC4 and CYP1B1.
Kurzawski M, Dziedziejko V, Post M, Wójcicki M, Urasińska E, Miętkiewski J, Droździk M. Kurzawski M, et al. Pharmacol Rep. 2012;64(4):927-39. doi: 10.1016/s1734-1140(12)70888-5. Pharmacol Rep. 2012. PMID: 23087145 Free article.
The most spectacular increases in expression were observed with ABCC4 (MRP4) - at the mRNA level, and CYP1B1 - at both the mRNA and protein levels. ...
The most spectacular increases in expression were observed with ABCC4 (MRP4) - at the mRNA level, and CYP1B1 - at both the mRNA and p …
Bioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer Therapy.
Ho PY, Duan Z, Batra N, Jilek JL, Tu MJ, Qiu JX, Hu Z, Wun T, Lara PN, DeVere White RW, Chen HW, Yu AM. Ho PY, et al. J Pharmacol Exp Ther. 2018 Jun;365(3):494-506. doi: 10.1124/jpet.118.247775. Epub 2018 Mar 30. J Pharmacol Exp Ther. 2018. PMID: 29602831 Free PMC article.
Here we first report a new ncRNA bioengineering technology using more stable ncRNA carrier (nCAR) containing a pre-miR-34a derivative identified by rational design and experimental validation. This approach offered a remarkable higher level expression (40%-80% of total RNA …
Here we first report a new ncRNA bioengineering technology using more stable ncRNA carrier (nCAR) containing a pre-miR-34a derivative identi …
Multidrug transporter MRP4/ABCC4 as a key determinant of pancreatic cancer aggressiveness.
Sahores A, Carozzo A, May M, Gómez N, Di Siervi N, De Sousa Serro M, Yaneff A, Rodríguez-González A, Abba M, Shayo C, Davio C. Sahores A, et al. Sci Rep. 2020 Aug 26;10(1):14217. doi: 10.1038/s41598-020-71181-w. Sci Rep. 2020. PMID: 32848164 Free PMC article.
Contrarily, MRP4 overexpression significantly increased BxPC-3 growth rate, produced a switch in the expression of EMT markers, and enhanced experimental metastatic incidence. Altogether, our results indicate that MRP4 is associated with a more aggressive phenotype in PDAC …
Contrarily, MRP4 overexpression significantly increased BxPC-3 growth rate, produced a switch in the expression of EMT markers, and enhanced …
Mechanistic study on hepatocarcinogenesis of piperonyl butoxide in mice.
Kawai M, Saegusa Y, Jin M, Dewa Y, Nishimura J, Harada T, Shibutani M, Mitsumori K. Kawai M, et al. Toxicol Pathol. 2009 Oct;37(6):761-9. doi: 10.1177/0192623309344087. Epub 2009 Aug 18. Toxicol Pathol. 2009. PMID: 19690152
Real-time reverse transcription-polymerase chain reaction (RT-PCR) analysis showed up-regulation of genes related to metabolism, such as cytochrome P450 1A1 and 2B10, and metabolic stress, such as Por, Nqo1, Nrf2, abcc3, and abcc4. Early responsive genes downstream of mito …
Real-time reverse transcription-polymerase chain reaction (RT-PCR) analysis showed up-regulation of genes related to metabolism, such as cyt …
Factors Influencing Mortality in Children with Central Nervous System Tumors: A Cohort Study on Clinical Characteristics and Genetic Markers.
Torres-Espíndola LM, Pérez-De Marcos JC, Castillejos-López M, Velasco-Hidalgo L, Cárdenas-Cardós R, De Uña-Flores A, Salinas-Lara C, Caballero-Salazar S, Fernández-Plata R, Aquíno-Gálvez A. Torres-Espíndola LM, et al. Genes (Basel). 2024 Apr 9;15(4):473. doi: 10.3390/genes15040473. Genes (Basel). 2024. PMID: 38674407
This study investigated the clinical characteristics and single nucleotide variant (SNV) in ABCB1, ABCC1, ABCC2, ABCC4, and ABCG2, and their association with mortality in pediatric patients with central nervous system tumors (CNST). ...
This study investigated the clinical characteristics and single nucleotide variant (SNV) in ABCB1, ABCC1, ABCC2, ABCC4, and ABCG2, an …
Glutathione pathway genetic polymorphisms and lung cancer survival after platinum-based chemotherapy.
Moyer AM, Sun Z, Batzler AJ, Li L, Schaid DJ, Yang P, Weinshilboum RM. Moyer AM, et al. Cancer Epidemiol Biomarkers Prev. 2010 Mar;19(3):811-21. doi: 10.1158/1055-9965.EPI-09-0871. Epub 2010 Mar 3. Cancer Epidemiol Biomarkers Prev. 2010. PMID: 20200426 Free PMC article.
RESULTS: We observed suggestive associations between survival and GSTT1 copy number (P = 0.017), and GSTA5, GSTM4, and ABCC4 SNPs, adjusted for covariates (P = 0.018, 0.002, and 0.002, respectively) or not (P = 0.005, 0.011, and 0.002). ...CONCLUSIONS: These results sugges …
RESULTS: We observed suggestive associations between survival and GSTT1 copy number (P = 0.017), and GSTA5, GSTM4, and ABCC4 SNPs, ad …
Identification of MRP4/ABCC4 as a Target for Reducing the Proliferation of Pancreatic Ductal Adenocarcinoma Cells by Modulating the cAMP Efflux.
Carozzo A, Yaneff A, Gómez N, Di Siervi N, Sahores A, Diez F, Attorresi AI, Rodríguez-González Á, Monczor F, Fernández N, Abba M, Shayo C, Davio C. Carozzo A, et al. Mol Pharmacol. 2019 Jul;96(1):13-25. doi: 10.1124/mol.118.115444. Epub 2019 May 1. Mol Pharmacol. 2019. PMID: 31043460
Our data highlight the MRP4-dependent cAMP extrusion process as a key participant in cell proliferation, indicating that MRP4 could be an exploitable therapeutic target for PDAC. SIGNIFICANCE STATEMENT: ABCC4/MRP4 is the main transporter responsible for cAMP efflux. In thi …
Our data highlight the MRP4-dependent cAMP extrusion process as a key participant in cell proliferation, indicating that MRP4 could be an ex …
17 results